Template plasmid integration in germline genome-edited cattle

Nat Biotechnol. 2020 Feb;38(2):163-164. doi: 10.1038/s41587-019-0394-6. Epub 2020 Feb 7.

Authors

Alexis L Norris^#¹, Stella S Lee^#¹, Kevin J Greenlees¹, Daniel A Tadesse², Mayumi F Miller², Heather A Lombardi³

Affiliations

¹ Office of New Animal Drug Evaluation, US Food and Drug Administration, Center for Veterinary Medicine, Rockville, MD, USA.
² Office of Research, Center for Veterinary Medicine, US Food and Drug Administration, Laurel, MD, USA.
³ Office of New Animal Drug Evaluation, US Food and Drug Administration, Center for Veterinary Medicine, Rockville, MD, USA. Heather.Lombardi@fda.hhs.gov.

^# Contributed equally.

PMID: 32034391
DOI: 10.1038/s41587-019-0394-6

No abstract available

Publication types

Letter

MeSH terms

Animals
Cattle / genetics*
Genome*
Germ Cells / metabolism*
Mutagenesis, Insertional / genetics
Plasmids / genetics*
Templates, Genetic*