A novel inflatable left ventricular partitioning device

Ying Chen; Wenchang Tan

doi:10.1016/j.mehy.2020.109571

A novel inflatable left ventricular partitioning device

Med Hypotheses. 2020 May:138:109571. doi: 10.1016/j.mehy.2020.109571. Epub 2020 Jan 14.

Authors

Ying Chen¹, Wenchang Tan²

Affiliations

¹ Shenzhen Graduate School, Peking University, Shenzhen, China; College of Engineering, Peking University, Beijing, China. Electronic address: chenying2018@pku.edu.cn.
² Shenzhen Graduate School, Peking University, Shenzhen, China; College of Engineering, Peking University, Beijing, China. Electronic address: tanwch@pku.edu.cn.

PMID: 32028194
DOI: 10.1016/j.mehy.2020.109571

Abstract

Percutaneous ventricular restoration (PVR) is an established treatment for patients with combined ischemic coronary artery disease and hear failure (HF). The left ventricle (LV) partitioning device is an interventional medical device that can be implanted into the ventricles of patients to reduce LV volumes, resulting in improved LV remodeling. However, the isolation surface area of the device is invariant, while the LV size of each patient is different. Thus, we designed a novel inflatable LV partitioning device. The functional volume of our ventricular isolation device can be adjusted by inflating and exhausting the device via the stomata based on a patient's ventricle size. The novel design could potentially reduce ventricular functional volume and improve the LV hemodynamic environment, thus resulting in favorable outcomes with reassuring safety and efficacy.

Keywords: Heart failure; LV partitioning device; Parachute device; Percutaneous ventricular restoration.

MeSH terms

Heart Failure* / therapy
Heart Ventricles*
Humans
Prostheses and Implants
Treatment Outcome
Ventricular Remodeling