Repeated viral meningitis in a newborn

J Neurovirol. 2020 Jun;26(3):449-451. doi: 10.1007/s13365-020-00829-0. Epub 2020 Feb 5.

Abstract

Human enteroviruses (EV) are the most common cause of viral meningitis in children. Human parechoviruses (HPeV) are increasingly being recognized as a cause of central nervous system (CNS) infections and sepsis-like disease in children. Both viruses belong to Picornaviridae family. The clinical picture in EV and HPeV infections is usually nonspecific. Therefore, molecular detection of both viruses is needed for etiological diagnosis. In this case report, we describe and discuss clinical and laboratory findings of two consecutive episodes of viral meningitis caused by EV and HPeV, respectively, occurring in the first month of a newborn's life.

Keywords: CNS infections; Enterovirus; Meningitis; Parechovirus; Pleocytosis.

Publication types

  • Case Reports

MeSH terms

  • Enterovirus B, Human / classification
  • Enterovirus B, Human / genetics*
  • Enterovirus B, Human / isolation & purification
  • Enterovirus B, Human / pathogenicity
  • Female
  • Humans
  • Infant, Newborn
  • Meningitis, Viral / diagnosis*
  • Meningitis, Viral / pathology
  • Meningitis, Viral / virology
  • Parechovirus / classification
  • Parechovirus / genetics*
  • Parechovirus / isolation & purification
  • Parechovirus / pathogenicity
  • Picornaviridae Infections / diagnosis*
  • Picornaviridae Infections / pathology
  • Picornaviridae Infections / virology
  • RNA, Viral / genetics*
  • Recurrence
  • Reverse Transcriptase Polymerase Chain Reaction
  • Sepsis / diagnosis*
  • Sepsis / pathology
  • Sepsis / virology
  • Sequence Analysis, DNA

Substances

  • RNA, Viral