Non-Enzymatic Amperometric Glucose Sensor Based on Carbon Nanodots and Copper Oxide Nanocomposites Electrode

Tharinee Sridara; Jantima Upan; Gopalan Saianand; Adisorn Tuantranont; Chanpen Karuwan; Jaroon Jakmunee

doi:10.3390/s20030808

Non-Enzymatic Amperometric Glucose Sensor Based on Carbon Nanodots and Copper Oxide Nanocomposites Electrode

Sensors (Basel). 2020 Feb 2;20(3):808. doi: 10.3390/s20030808.

Authors

Tharinee Sridara^{1

2}, Jantima Upan^{1

2}, Gopalan Saianand³, Adisorn Tuantranont^{4

5}, Chanpen Karuwan⁵, Jaroon Jakmunee^{1

5

6}

Affiliations

¹ Department of Chemistry, Faculty of Science, Chiang Mai University, Chiang Mai 50200, Thailand.
² The Graduate School, Chiang Mai University, Chiang Mai 50200, Thailand.
³ Faculty of Science, The University of Newcastle, Callaghan, NSW 2308, Australia.
⁴ National Security and Dual-Use Technology Center, National Science and Technology Development Agency, Pathumthani 12120, Thailand.
⁵ Center of Advanced Materials of Printed Electronics and Sensors, Materials Science Research Center, Faculty of Science, Chiang Mai University, Chiang Mai 50200, Thailand.
⁶ Center of Excellence for Innovation in Chemistry and Research Center on Chemistry for Development of Health Promoting Products from Northern Resources, Faculty of Science, Chiang Mai University, Chiang Mai 50200, Thailand.

Abstract

In this research work, a non-enzymatic amperometric sensor for the determination of glucose was designed based on carbon nanodots (C-dots) and copper oxide (CuO) nanocomposites (CuO-C-dots). The CuO-C-dots nanocomposites were modified on the surface of a screen-printed carbon electrode (SPCE) to increase the sensitivity and selectivity of the glucose sensor. The as-synthesized materials were further analyzed for physico-chemical properties through characterization tools such as transmission electron microscopy (TEM) and Fourier-transform infrared spectroscopy (FTIR); and their electrochemical performance was also studied. The SPCE modified with CuO-C-dots possess desirable electrocatalytic properties for glucose oxidation in alkaline solutions. Moreover, the proposed sensing platform exhibited a linear range of 0.5 to 2 and 2 to 5 mM for glucose detection with high sensitivity (110 and 63.3 µA mM^-1cm^-2), and good selectivity and stability; and could potentially serve as an effective alternative method of glucose detection.

Keywords: amperometry; carbon nanodots; copper oxide; glucose sensor; non-enzymatic.

Abstract

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