Background: Symptomatic popliteal artery aneurysms (PAAs) can be managed by open surgery or endovascular exclusion.
Methods: The authors describe a case of a 68-mm PAA causing compressive symptoms and managed by endovascular exclusion combined with percutaneous sac decompression.
Results: Endovascular exclusion allows sac pressure reduction. Additional percutaneous sac aspiration and thrombin injection promote sac shrinking and avoid persistent collateral flow.
Conclusions: In challenging cases, matching different techniques can be helpful.
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