Passive microwave radiometry in biomedical studies

Drug Discov Today. 2020 Apr;25(4):757-763. doi: 10.1016/j.drudis.2020.01.016. Epub 2020 Jan 28.

Abstract

Passive microwave radiometry (MWR) measures natural emissions in the range 1-10GHz from proteins, cells, organs and the whole human body. The intensity of intrinsic emission is determined by biochemical and biophysical processes. The nature of this process is still not very well known. Infrared thermography (IRT) can detect emission several microns deep (skin temperature), whereas MWR allows detection of thermal abnormalities down to several centimeters (internal or deep temperature). MWR is noninvasive and inexpensive. It requires neither fluorescent nor radioactive labels, nor ionizing or other radiation. MWR can be used in early drug discovery as well as preclinical and clinical studies.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Body Temperature / physiology
  • Clinical Trials as Topic / methods
  • Drug Discovery / methods*
  • Drug Evaluation, Preclinical / methods
  • Humans
  • Microwaves*
  • Radiometry / methods*
  • Thermography / methods