TP53 mutated AML subclones exhibit engraftment in a humanized bone marrow ossicle mouse model

Ann Hematol. 2020 Mar;99(3):653-655. doi: 10.1007/s00277-020-03920-y. Epub 2020 Jan 30.
No abstract available

Publication types

  • Letter

MeSH terms

  • Animals
  • Bone Marrow Transplantation*
  • Heterografts
  • Humans
  • Leukemia, Myeloid, Acute* / genetics
  • Leukemia, Myeloid, Acute* / metabolism
  • Leukemia, Myeloid, Acute* / pathology
  • Mice
  • Mice, Inbred NOD
  • Mice, SCID
  • Mutation*
  • Neoplasm Transplantation*
  • Neoplasms, Experimental* / genetics
  • Neoplasms, Experimental* / metabolism
  • Neoplasms, Experimental* / pathology
  • Tumor Suppressor Protein p53* / genetics
  • Tumor Suppressor Protein p53* / metabolism

Substances

  • TP53 protein, human
  • Tumor Suppressor Protein p53