Selection criteria of solid organ donors in relation to infectious diseases: A Spanish consensus

Transplant Rev (Orlando). 2020 Apr;34(2):100528. doi: 10.1016/j.trre.2020.100528. Epub 2020 Jan 13.

Abstract

The immunosuppressive treatment that recipients receive from a solid organ transplantation hinders the defensive response to infection. Its transmission from the donor can cause dysfunction or loss of the graft and even death of the recipient if proper preventive measures are not established. This potential risk should be thoroughly evaluated to minimise the risk of infection transmission from donor to recipient, especially with organ transplantation from donors with infections, without increasing graft dysfunction and morbidity and mortality in the recipient. This document aims to review current knowledge about infection screening in potential donors and offer clinical and microbiological recommendations about the use of organs from donors with infection based on available scientific evidence.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Allografts / microbiology
  • Consensus
  • Donor Selection
  • Humans
  • Immunocompromised Host
  • Infections / epidemiology*
  • Infections / etiology
  • Infections / transmission
  • Mass Screening
  • Organ Transplantation*
  • Postoperative Complications / epidemiology*
  • Spain / epidemiology