An Influenza Virus Hemagglutinin Computationally Optimized Broadly Reactive Antigen Elicits Antibodies Endowed with Group 1 Heterosubtypic Breadth against Swine Influenza Viruses

J Virol. 2020 Mar 31;94(8):e02061-19. doi: 10.1128/JVI.02061-19. Print 2020 Mar 31.

Authors

Amanda L Skarlupka¹, Z Beau Reneer¹, Rodrigo B Abreu¹, Ted M Ross^{1

2}, Giuseppe A Sautto³

Affiliations

¹ Center for Vaccines and Immunology, University of Georgia, Athens, Georgia, USA.
² Department of Infectious Diseases, University of Georgia, Athens, Georgia, USA.
³ Center for Vaccines and Immunology, University of Georgia, Athens, Georgia, USA gasautto@uga.edu.

No abstract available

Keywords: COBRA; influenza vaccine; influenza virus; monoclonal antibodies; swine influenza virus.

Publication types

Letter

MeSH terms

Animals
Antibodies, Monoclonal / immunology
Antibodies, Viral / immunology
Hemagglutinin Glycoproteins, Influenza Virus / immunology
Hemagglutinins, Viral / immunology*
Humans
Influenza A Virus, H1N1 Subtype / immunology*
Influenza Vaccines
Influenza, Human / virology

Substances

Antibodies, Monoclonal
Antibodies, Viral
Hemagglutinin Glycoproteins, Influenza Virus
Hemagglutinins, Viral
Influenza Vaccines