Modified surgical drilling protocols influence osseointegration performance and predict value of implant stability parameters during implant healing process

Haw-Ming Huang; Tze-Jian Chee; Wei-Zhen Lew; Sheng-Wei Feng

doi:10.1007/s00784-020-03215-6

Modified surgical drilling protocols influence osseointegration performance and predict value of implant stability parameters during implant healing process

Clin Oral Investig. 2020 Oct;24(10):3445-3455. doi: 10.1007/s00784-020-03215-6. Epub 2020 Jan 27.

Authors

Haw-Ming Huang^{1

2}, Tze-Jian Chee¹, Wei-Zhen Lew¹, Sheng-Wei Feng^{3

4

5}

Affiliations

¹ School of Dentistry, College of Oral Medicine, Taipei Medical University, Taipei, Taiwan.
² Graduate Institute of Biomedical Optomechatronics, College of Biomedical Engineering, Taipei Medical University, Taipei, Taiwan.
³ School of Dentistry, College of Oral Medicine, Taipei Medical University, Taipei, Taiwan. shengwei@tmu.edu.tw.
⁴ Division of Prosthodontics, Department of Dentistry, Taipei Medical University Hospital, Taipei, Taiwan. shengwei@tmu.edu.tw.
⁵ School of Oral Hygiene, College of Oral Medicine, Taipei Medical University, 250 Wu-Hsing Street, Taipei, Taiwan. shengwei@tmu.edu.tw.

PMID: 31989368
DOI: 10.1007/s00784-020-03215-6

Abstract

Objective: The aim of this study was to evaluate the effects of three different surgical drilling protocols on changes of implant stability parameters and osseointegration performance during the healing period in rabbit femoral condyles.

Material and methods: Thirty New Zealand white rabbits were used in this study. Three experimental groups according to different surgical drilling protocols (undersized, standard and oversized preparation) were designed. Measurements of implant stability parameters were performed immediately after implant insertion and then at 1, 2, 4, and 8 weeks after the operation. After the animals were sacrificed, the bone blocks with implant were prepared for histological evaluation and histomorphometric analysis.

Results: The results demonstrated that the ISQ values of each group increased gradually through the whole healing period, while the damping factor showed the opposite tendency. The histomorphometric analysis revealed that BIC (bone-implant contact) values gradually increased with time until 8 weeks of healing at each group. In addition, the undersized group has the highest initial BIC (25.16% ± 7.25%) and the lowest values were found in oversized group (9.13% ± 5.89%). Moreover, a higher correlation (R² = 0. 9817) between ISQ and BIC values in oversized group and moderate correlations between DF and BIC values in undersized group (R² = 0.823) were demonstrated.

Conclusions: The undersized drilling protocol group presented the highest implant stability and BIC values in the whole healing period, while the similar tendency of results was found between standard and oversized drilling protocol groups.

Clinical relevance: These results suggested that undersized drilling protocol is mechanically and biologically beneficial in low-density bone. The modifications of surgical drilling protocols would influence the predictive value of implant stability parameters for osseointegration performance.

Keywords: Implant stability; Osseointegration; Rabbit femoral condyle; Undersized drilling protocol.

MeSH terms

Animals
Bone and Bones
Dental Implantation, Endosseous
Dental Implants
Osseointegration*
Rabbits
Wound Healing

Substances

Dental Implants