Nanoformulations for Ocular Delivery of Drugs - A Patent Perspective

Recent Pat Drug Deliv Formul. 2019;13(4):255-272. doi: 10.2174/1872211314666200127101149.

Abstract

Efficient delivery of ocular therapeutics with improved efficacy, enhanced bioavailability, and acceptable patient compliance presents unique challenges. This can be attributed to the presence of protective mechanisms, physicobiological barriers, and structural obstacles in the eye. Nanotherapeutic interventions have been explored extensively over the past few years to overcome these limitations. The present review focusses on the nanoformulations developed for the diagnosis and treatment of various ocular diseases besides providing an in-depth insight into the patents reported for the same.

Keywords: Ocular; nanoemulsions; nanoformulations; nanolipid carriers; nanoparticles; nanotechnology; solid lipid carriers..

Publication types

  • Review

MeSH terms

  • Animals
  • Biological Availability
  • Drug Delivery Systems*
  • Eye Diseases / diagnosis
  • Eye Diseases / drug therapy*
  • Humans
  • Medication Adherence
  • Nanoparticles*
  • Patents as Topic