Copper-mediated tandem ring-opening/cyclization reactions of cyclopropanols with aryldiazonium salts: synthesis of N-arylpyrazoles

Chem Commun (Camb). 2020 Feb 18;56(14):2202-2205. doi: 10.1039/c9cc09657d. Epub 2020 Jan 24.

Abstract

A general method for the synthesis of structurally diverse N-arylpyrazoles from readily available cyclopropanols and aryldiazonium salts is disclosed. The reaction was conducted at room temperature within minutes with a broad substrate scope and excellent regioselectivity.