An update on the role of 18F-FDG-PET/CT in major infectious and inflammatory diseases

Am J Nucl Med Mol Imaging. 2019 Dec 15;9(6):255-273. eCollection 2019.

Abstract

For decades, conventional nuclear medicine techniques have been utilized for the assessment of many infectious and inflammatory diseases. Most of these techniques have limitations such as the relatively low spatial resolution, being time consuming and low sensitivity or specificity. In recent years, FDG-PET/CT has shown promising role in the management of such diseases. An expanding set of studies illustrate the multifarious roles of FDG-PET/CT in the assessment of these conditions, both systemic diseases and more regional. Specifically, PET can provide vital information at a molecular level and consequently detect the disease activity at their earliest manifestation. With the continuing research on the diagnosis and treatment monitoring of patients with infectious and inflammatory diseases, the role of PET/CT can be further extended.

Keywords: FDG PET/CT; HIV; bone infection; fever of unknown origin; infectious disease; inflammatory disease; sarcoidosis; tuberculosis; vasculitis.

Publication types

  • Review