Synthesis of 3,4-Dihydropyrano[c]chromenes Using Carbon Microsphere Supported Copper Nanoparticles (Cu-NP/C) Prepared from Loaded Cation Exchange Resin as a Catalyst

Yogesh W More; Sunil U Tekale; Nitishkumar S Kaminwar; László Kótai; Tibor Pasinszki; Pravin S Kendrekar; Rajendra P Pawar

doi:10.2174/1570179415666181116104931

Synthesis of 3,4-Dihydropyrano[c]chromenes Using Carbon Microsphere Supported Copper Nanoparticles (Cu-NP/C) Prepared from Loaded Cation Exchange Resin as a Catalyst

Curr Org Synth. 2019;16(2):288-293. doi: 10.2174/1570179415666181116104931.

Authors

Yogesh W More¹, Sunil U Tekale¹, Nitishkumar S Kaminwar², László Kótai³, Tibor Pasinszki⁴, Pravin S Kendrekar⁵, Rajendra P Pawar¹

Affiliations

¹ Department of Chemistry, Deogiri College, Aurangabad 431005 (Maharashtra), India.
² Lal Bahadur Shastri Mahavidyalaya, Dharmabad, Nanded (Maharashtra), India.
³ Research Centre for Natural Sciences, Hungarian Academy of Sciences, Budapest, H-1519, Hungary.
⁴ Department of Chemistry, School of Pure Sciences, College of Engineering, Science & Technology, Fiji National University, Nasinu 7222, Fiji.
⁵ Department of Health Sciences, Central University of Technology, Bloemfontein, Free State-9300, South Africa.

PMID: 31975678
DOI: 10.2174/1570179415666181116104931

Abstract

Aim and objective: The present study was performed with the aim to develop an efficient and environmentally benign protocol for the synthesis of biologically siginifcant 3, 4-dihydropyrano[c]chromenes using a new catalytic material. The protocol involves the use of a reusable, environment friendly materials and solvents with operational simplicity.

Materials and methods: Carbon microsphere supported copper nanoparticles (Cu-NP/C) prepared from loaded cation exchange resin were synthesized, characterized with well versed analytical techniques such as XRD, SEM and Raman spectroscopy and the synthesized material was used as a catalyst for the environmentally benign synthesis of 3,4-dihydropyrano[c]chromenes.

Results: The formation of carbon microsphere supported copper nanoparticles (Cu-NP/C) prepared from loaded cation exchange resin was confirmed by XRD, SEM and Raman spectroscopy which was employed as a heterogeneous material for the synthesis of 3,4-dihydropyrano[c]chromenes. The products formed were characterized by the analysis of spectroscopic data - NMR, IR and mass. The safe catalytic system offers several advantages including operational simplicity, environmental friendliness, high yield, and reusability of catalyst and green chemical transformation.

Conclusion: Herein we report an easy and efficient protocol for the one-pot synthesis of dihydropyrano[ c]chromenes using environmentally benign MCR approach in ethanol as the green solvent. The method developed herein constitutes a valuable addition to the existing methods for the synthesis of titled compounds.

Keywords: Cu-NP/C; catalyst; dihydropyrano[c]chromenes; green solvent; multicomponent reaction; one-pot synthesis.