Magnetic Dextran Nanoparticles That Bear Hydrophilic Porphyrin Derivatives: Bimodal Agents for Potential Application in Photodynamic Therapy

Jean-Pierre Mbakidi; Frédérique Brégier; Tan-Sothea Ouk; Robert Granet; Sandra Alves; Eric Rivière; Sylviane Chevreux; Gilles Lemercier; Vincent Sol

doi:10.1002/cplu.201500361

Magnetic Dextran Nanoparticles That Bear Hydrophilic Porphyrin Derivatives: Bimodal Agents for Potential Application in Photodynamic Therapy

Chempluschem. 2015 Sep;80(9):1367. doi: 10.1002/cplu.201500361. Epub 2015 Aug 26.

Authors

Affiliations

¹ Laboratoire de Chimie des Substances Naturelles EA 1069, Université de Limoges, Faculté des Sciences et Techniques, 123 Av. Albert Thomas, 87060 Limoges (France).
² Equipe de Spectrométrie de masse (Chimie Structurale Organique et Biologique), IPCM, UMR8232, Université Pierre et Marie Curie, 4 Place Jussieu, 75252 Paris CEDEX 05 (France).
³ Institut de Chimie Moléculaire des Matériaux Organiques, Equipe de Chimie Inorganique, UMR 8182 CNRS, Université Paris sud, 91405 Orsay (France).
⁴ Université de Reims Champagne Ardenne, ICMR UMR CNRS 7312, BP 1039, 51687 Reims CEDEX 2 (France).
⁵ "Médicaments photoactivables-photochimiothérapie" (PHOTOMED; France), GDR CNRS 3049.

PMID: 31973358
DOI: 10.1002/cplu.201500361

Abstract

Invited for this month's cover is the group of Prof. Vincent Sol from the University of Limoges, France. This study is a collaboration between the Universities of Limoges, Reims, Pierre et Marie Curie (UPMC, Paris), and Paris Sud (Orsay). The cover picture shows a magnetic dextran nanoparticle bearing hydrophilic porphyrin derivatives; the illustration shows bimodal nanoplatforms that could be used as contrast agents in magnetic resonance imaging as well as photosensitizers in photodynamic therapy. Read the full text of the article at 10.1002/cplu.201500087.