A Review on Studies of Marijuana for Alzheimer's Disease - Focusing on CBD, THC

Seok Hee Kim; Jin Won Yang; Kyung Han Kim; Jong Uk Kim; Tae Han Yook

doi:10.3831/KPI.2019.22.030

A Review on Studies of Marijuana for Alzheimer's Disease - Focusing on CBD, THC

J Pharmacopuncture. 2019 Dec;22(4):225-230. doi: 10.3831/KPI.2019.22.030. Epub 2019 Dec 31.

Authors

Seok Hee Kim¹, Jin Won Yang², Kyung Han Kim³, Jong Uk Kim¹, Tae Han Yook¹

Affiliations

¹ Department of Acupuncture & Moxibustion Medicine, Korean Medicine Hospital of Woosuk University, Jeonju, Korea.
² Department of Pharmacology, College of Pharmacy, Woosuk University, Wanju, Korea.
³ Department of Preventive Medicine, College of Korean Medicine, Woosuk University, Jeonju, Korea.

Abstract

Objectives: This study was to discuss the research trend of dementia treatment using cannabis for the purpose of providing the basis of cannabis use for medical purposes in the future.

Methods: This study searched publications, which were registered to databases or published by Aug 22, 2019, and targeted the full-text or abstracts of these publications. We selected the final nine studies met all selection criteria.

Results: These results implied that the CBD components of cannabis might be useful to treat and prevent AD because CBD components could suppress the main causal factors of AD. Moreover, it was suggested that using CBD and THC together could be more useful than using CBD or THC alone.

Conclusion: We hope that there will be a solid foundation to use cannabis for medical use by continuously evaluating the possibility of using cannabis for clinical purposes as a dementia treatment substance and cannabis can be used as a positive tool.

Keywords: AD(Alzheimer’s diseas); CBD(Cannabidiol); Marijuana; THC(Δ-tetrahydrocannabidiol).

Publication types

Review