Bone Marrow Examination: Why, How, and What to Expect from the Pathologist

Vet Clin North Am Equine Pract. 2020 Apr;36(1):35-52. doi: 10.1016/j.cveq.2019.11.002. Epub 2020 Jan 16.

Abstract

This article describes the indications for sampling of bone marrow, the technical aspects of obtaining marrow core biopsies and aspirates, and the preparation of marrow smears. All aspects are illustrated with clinical cases. The information that can be expected from the pathologist's report of marrow samples is outlined, and the clinical features and prognosis of different types of leukemia are detailed.

Keywords: Anemia; Cytopenia; Equine; Horse; Leukemia; Leukopenia; Myeloid neoplasia; Thrombocytopenia.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Animals
  • Bone Marrow / pathology*
  • Bone Marrow Diseases / blood
  • Bone Marrow Diseases / pathology
  • Bone Marrow Diseases / veterinary*
  • Female
  • Horse Diseases / blood
  • Horse Diseases / pathology*
  • Horses / blood*
  • Leukemia / blood
  • Leukemia / pathology
  • Leukemia / veterinary
  • Pathology, Clinical
  • Prognosis
  • Specimen Handling