A feasible sonochemical approach to synthesize CuO@CeO2 nanomaterial and their enhanced non-enzymatic sensor performance towards neurotransmitter

Tse-Wei Chen; Sathishkumar Chinnapaiyan; Shen-Ming Chen; M Ajmal Ali; Mohamed Soliman Elshikh; Ahmed Hossam Mahmoud

doi:10.1016/j.ultsonch.2019.104903

A feasible sonochemical approach to synthesize CuO@CeO₂ nanomaterial and their enhanced non-enzymatic sensor performance towards neurotransmitter

Ultrason Sonochem. 2020 May:63:104903. doi: 10.1016/j.ultsonch.2019.104903. Epub 2019 Nov 26.

Authors

Tse-Wei Chen¹, Sathishkumar Chinnapaiyan², Shen-Ming Chen³, M Ajmal Ali⁴, Mohamed Soliman Elshikh⁴, Ahmed Hossam Mahmoud⁵

Affiliations

¹ Department of Chemical Engineering and Biotechnology, National Taipei University of Technology, No. 1, Section 3, Chung-Hsiao East Road, Taipei 106, Taiwan, Republic of China; Research and Development Center for Smart Textile Technology, National Taipei University of Technology, Taipei, Taiwan, Republic of China.
² Department of Chemical Engineering and Biotechnology, National Taipei University of Technology, No. 1, Section 3, Chung-Hsiao East Road, Taipei 106, Taiwan, Republic of China.
³ Department of Chemical Engineering and Biotechnology, National Taipei University of Technology, No. 1, Section 3, Chung-Hsiao East Road, Taipei 106, Taiwan, Republic of China. Electronic address: smchen78@ms15.hinet.net.
⁴ Department of Botany, College of Science, King Saud University, P.O Box 2455, Riyadh 11451, Saudi Arabia.
⁵ Department Zoology, College of Science, King Saud University, P.O Box 2455, Riyadh 11451, Saudi Arabia.

PMID: 31951999
DOI: 10.1016/j.ultsonch.2019.104903

Abstract

A nanostructured and high conductive cupric oxide (CuO NPs) with hierarchical CeO₂ sheets-like structure was synthesized by a facile sonochemical approach. Furthermore, CuO/CeO₂ nanostructure is synthesized by high-intensity ultrasonic probe (Ti-horn, 50 kHz and 100 W) at ambient air. Moreover, the synthesized CuO/CeO₂ material was characterized by various analytical techniques including FESEM, EDX, XRD and electrochemical methods. Then, the synthesized CuO/CeO₂ composite was applied for the electrocatalytic detection of dopamine using CV and DPV techniques. In addition, the CuO/CeO₂ modified electrode has good electrocatalytic performance with high linear range from 0.025 to 98.5 µM towards the determination of dopamine drug and high sensitivity of the CuO/CeO₂ modified drug sensor was calculated as 16.34 nM and 4.823 μA·µM^-1·cm^-2, respectively. Moreover, a repeatability, reproducibility and stability of the CuO@CeO₂ mixture modified electrode were analyzed towards the determination of dopamine biomolecule. Interestingly, the real time application of CuO@CeO₂ modified electrode was established in different serum and drug samples.

Keywords: Copper oxide nanosheets; Dopamine sensor; Electrochemical sensor; Modified electrode; Ultrasound approach.

MeSH terms

Cerium / chemistry*
Copper / chemistry*
Dielectric Spectroscopy
Feasibility Studies
Microscopy, Electron, Scanning
Neurotransmitter Agents / chemistry*
Reproducibility of Results
Sonication*
Spectrometry, X-Ray Emission
X-Ray Diffraction

Substances

Neurotransmitter Agents
Cerium
ceric oxide
Copper
cupric oxide