LR-selHSQMBC: Simultaneous Detection and Quantification of Very Weak Long-Range Heteronuclear NMR Correlations

Kumar Motiram-Corral; Alexandre A Souza; Josep Saurí; Pau Nolis; Teodor Parella

doi:10.1002/cphc.201901142

LR-selHSQMBC: Simultaneous Detection and Quantification of Very Weak Long-Range Heteronuclear NMR Correlations

Chemphyschem. 2020 Feb 17;21(4):280-283. doi: 10.1002/cphc.201901142. Epub 2020 Jan 22.

Authors

Kumar Motiram-Corral¹, Alexandre A Souza², Josep Saurí³, Pau Nolis¹, Teodor Parella¹

Affiliations

¹ Servei de Ressonància Magnètica Nuclear, Universitat Autònoma de Barcelona, E-08193 Bellaterra, Barcelona (Catalonia, Spain.
² Departamento de Química, Universidade Federal de Piauí, 64049-550, Teresina" PI, Brazil.
³ Structure Elucidation Group, Analytical Research & Development, Merck & Co., Inc., 33 Av. Louis Pasteur, Boston, MA, 02215, USA.

PMID: 31951093
DOI: 10.1002/cphc.201901142

Abstract

The optimum detection and accurate measurement of longer-range (⁴ J and higher) heteronuclear NMR correlations is described. The magnitude and/or the sign of a wide range of large and small long-range couplings can be simultaneously determined for protonated and non-protonated ¹³ C and ¹⁵ N nuclei using the LR-selHSQMBC experiment.

Keywords: NMR spectroscopy; heteronuclear coupling constants; long-range heteronuclear connectivities; proton-deficient molecules structure elucidation; time-sharing NMR.

Publication types

Research Support, Non-U.S. Gov't

Abstract

Publication types

Grants and funding