Corneoconjunctival transposition for the treatment of deep stromal to full-thickness corneal defects in dogs: A multicentric retrospective study of 100 cases (2012-2018)

Vet Ophthalmol. 2020 May;23(3):450-459. doi: 10.1111/vop.12740. Epub 2020 Jan 16.

Abstract

Objective: To describe and evaluate the use of corneoconjunctival transposition (CTT) as a surgical treatment for canine deep stromal ulcers, descemetoceles, and full-thickness corneal defects and to determine its efficacy in preserving corneal graft transparency and vision.

Animals studied: One hundred client-owned dogs with deep stromal ulcers, descemetoceles, or full-thickness corneal defects.

Methods: Medical records of canine patients that underwent CCT, from 2012 to 2018, were reviewed. Only, patients with preoperative positive consensual pupillary light and dazzle reflexes were included.

Results: There were 59 males and 41 females, from 0.3 to 17 years. Brachycephalic breeds were overrepresented (65%). All patients were unilaterally affected, with 16 deep stromal ulcers, 33 descemetoceles, and 51 corneal perforations, of a median (range) size of 4 (2-8) mm. The central cornea was affected in the majority of cases (57%), and euryblepharon and keratoconjunctivitis sicca were the most common concurrent ocular diseases (42% and 40%, respectively). The graft was most frequently harvested from dorsal (67%), and 9/0 absorbable suture material was used. Intraoperative and postoperative complications were seen in 7 and 21 cases, respectively. Mean follow-up time was 107.8 days. Vision was preserved in 96% patients, with 62% showing faint to mild opacification. Among the statistically analyzed variables, euryblepharon and pigmentary keratitis were found to be significantly associated with greater corneal graft opacification (P = .040 and P = .028, respectively).

Conclusions: Corneoconjunctival transposition is an effective surgical treatment for deep stromal, descemetocele, and full-thickness corneal defects in dogs, achieving a highly satisfactory degree of corneal graft transparency and preserving vision.

Keywords: autograft; cornea; corneal surgery; graft rejection; keratoplasty; visual outcome.

Publication types

  • Multicenter Study

MeSH terms

  • Animals
  • Corneal Diseases / surgery
  • Corneal Diseases / veterinary*
  • Corneal Perforation / surgery
  • Corneal Perforation / veterinary*
  • Corneal Transplantation / veterinary*
  • Dog Diseases / surgery*
  • Dogs
  • Female
  • Male
  • Records / veterinary
  • Retrospective Studies
  • Spain
  • Treatment Outcome