Fluorescent Phosphorus Dendrimers: Towards Material and Biological Applications

Chempluschem. 2019 Aug;84(8):1070-1080. doi: 10.1002/cplu.201900337.

Abstract

Fluorescent derivatives of phosphorhydrazone dendrimers are reviewed. Diverse types of fluorophores have been used, such as pyrene, naphthol, anthracene, dansyl, diketone, phthalocyanine, maleimide, julolidine, rhodamine, fluorescein, or fluorene derivatives. The fluorescent groups can be located either as terminal groups on the surface, at the core, linked to the core (off-center), or to the branches of the dendritic structure. After fundamental research on their synthesis, these compounds have been used in the fields of catalysis, nanomaterials, OLEDs, sensors and biology/nanomedicine, in particular for monitoring transfection, or for their anti-inflammatory or anti-cancer properties.

Keywords: biology; dendrimers; fluorescence; nanostructures; synthesis design.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Anti-Inflammatory Agents / chemistry
  • Biocompatible Materials / chemistry
  • Dendrimers / chemistry*
  • Drug Carriers / chemistry
  • Fluorescent Dyes / chemistry*
  • Humans
  • Phosphorus / chemistry*

Substances

  • Anti-Inflammatory Agents
  • Biocompatible Materials
  • Dendrimers
  • Drug Carriers
  • Fluorescent Dyes
  • Phosphorus