Abstract
对HBV相关肝癌患者、乙型肝炎肝硬化患者、健康体检者（每组3例）血清外泌体进行深度测序,获取肝细胞癌特性性表达的miRNA基因共25个。其中上调的有17个，下调的基因有5个，选取5个基因进行qPCR验证，结果与筛选结果一致。.
Keywords:
Exosomes; HBV; Hepatocellular carcinoma; microRNA.
MeSH terms
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Biomarkers / blood*
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Carcinoma, Hepatocellular / diagnosis*
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Carcinoma, Hepatocellular / genetics
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Carcinoma, Hepatocellular / virology
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Exosomes*
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Hepatitis B / diagnosis*
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Hepatitis B / genetics
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Hepatitis B / virology
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Hepatitis B virus / genetics
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Humans
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Liver Neoplasms / diagnosis*
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Liver Neoplasms / genetics
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Liver Neoplasms / virology
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MicroRNAs / blood*
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MicroRNAs / genetics