Prevalence of REM sleep behavior disorder in Sun City, Arizona

David R Shprecher; Geidy E Serrano; Nan Zhang; Anthony Intorcia; Kathryn J Davis; Michael Glass; Jasmine Curry; Jessica Walker; Brett Cutler; Michael Callan; Angelica Garcia; Lucia I Sue; Thomas G Beach

doi:10.1016/j.heliyon.2019.e03140

Prevalence of REM sleep behavior disorder in Sun City, Arizona

Heliyon. 2020 Jan 9;6(1):e03140. doi: 10.1016/j.heliyon.2019.e03140. eCollection 2020 Jan.

Affiliations

¹ Cleo Roberts Center, Banner Sun Health Research Institute, Sun City, AZ, United States.
² Civin Laboratory for Neuropathology, Banner Sun Health Research Institute, Sun City, AZ, United States.
³ Department of Biostatistics, Mayo Clinic College of Medicine, Scottsdale, AZ, United States.

Abstract

Objective: To determine prevalence of REM sleep behavior disorder (RBD) [prodromal Lewy body disease] in Sun City, Arizona.

Patients and methods: We attempted, by telephone and mail, a survey using the RBD single item question for probable RBD (pRBD) and the Innsbruck RBD Inventory. Individuals answering "yes" to 4/5 Inventory questions were considered to have high likelihood RBD (HL-RBD.).

Results: Response rate was 484/3000 individuals contacted (16%), mean age 78; 48 (9.9%) endorsed pRBD by RBD1Q; 16 (3.3%) had HL-pRBD. Prevalence of idiopathic cases (without neurodegenerative disease) was 8.8% pRBD and 2.8% HL-RBD.

Conclusion: Our estimated definite RBD prevalence of 1.7% (61.3% of HL-RBD) was similar to previous community-based studies.

Keywords: Clinical research; Dementia with lewy bodies; Lewy body dementia; Nervous system; Neurology; Neuroscience; Parkinson disease; Pathology; REM sleep behavior disorder.