Endophlebectomy of the common femoral vein and endovascular iliac vein recanalization for chronic iliofemoral venous occlusion

J Vasc Surg Venous Lymphat Disord. 2020 Jul;8(4):572-582. doi: 10.1016/j.jvsv.2019.11.008. Epub 2020 Jan 10.

Abstract

Background: Chronic post-thrombotic occlusion of the iliofemoral veins causes significant morbidity, which can be alleviated if venous drainage is restored. We report our technique of surgical endophlebectomy and patchplasty of the common femoral vein (CFV) in conjunction with iliac vein stenting to restore venous flow from the infrainguinal venous system to the vena cava.

Methods: There were 157 patients who underwent CFV endophlebectomy combined with iliocaval recanalization. Questionnaires were completed both preoperatively and postoperatively to allow comparison. These included the Clinical, Etiology, Anatomy, and Pathophysiology clinical classification; the Venous Clinical Severity Score; the Villalta scale; the Venous Insufficiency Epidemiological and Economic Study on Quality of Life/Symptoms; and the 36-Item Short Form Health Survey quality of life questionnaire.

Results: Mean follow-up duration was 14.4 ± 2.9 months (range, 10-29 months). The mean preoperative Venous Clinical Severity Score was 15.3 ± 2.2, and this fell to 6.1 ± 1.8 after treatment (P < .001). The mean preoperative Villalta score dropped from 12.7 ± 2.6 to 6.3 ± 1.4 (P < .001). The quality of life and symptom severity scores were improved after 3 months by 17.2 points for quality of life (P < .001) and 20.5 points for symptom severity (P < .001). Primary patency was 81% (124/153) and secondary patency was 89.5% (137/153) at 12 months. Wound complications related to groin incision and lymphatic fistulas were observed in 22.8% (35/153) and 28.7% (44/153), respectively.

Conclusions: The hybrid operation of CFV endophlebectomy in conjunction with iliac vein recanalization should be considered a safe and effective treatment option in patients with severe post-thrombotic syndrome and iliofemoral veno-occlusive disease.

Keywords: Deep venous thrombosis; Endophlebectomy; Iliac vein stenting; Post-thrombotic syndrome; Quality of life.

MeSH terms

  • Adult
  • Aged
  • Angioplasty, Balloon* / adverse effects
  • Angioplasty, Balloon* / instrumentation
  • Chronic Disease
  • Combined Modality Therapy
  • Female
  • Femoral Vein / diagnostic imaging
  • Femoral Vein / physiopathology
  • Femoral Vein / surgery*
  • Humans
  • Iliac Vein* / diagnostic imaging
  • Iliac Vein* / physiopathology
  • Male
  • Middle Aged
  • Postthrombotic Syndrome / diagnostic imaging
  • Postthrombotic Syndrome / physiopathology
  • Postthrombotic Syndrome / therapy*
  • Quality of Life
  • Retrospective Studies
  • Stents
  • Time Factors
  • Treatment Outcome
  • Vascular Patency
  • Vascular Surgical Procedures* / adverse effects
  • Venous Thrombosis / diagnostic imaging
  • Venous Thrombosis / physiopathology
  • Venous Thrombosis / therapy*
  • Young Adult