Ultra-fast and visual detection of hydrazine hydrate based on a simple coumarin derivative

Shiqing Zhang; Ya Xie; Liqiang Yan

doi:10.1016/j.saa.2020.118028

Ultra-fast and visual detection of hydrazine hydrate based on a simple coumarin derivative

Spectrochim Acta A Mol Biomol Spectrosc. 2020 Apr 5:230:118028. doi: 10.1016/j.saa.2020.118028. Epub 2020 Jan 7.

Authors

Shiqing Zhang¹, Ya Xie¹, Liqiang Yan²

Affiliations

¹ College of Chemistry and Bioengineering, Guilin University of Technology, Guilin, Guangxi 541006, PR China.
² College of Chemistry and Bioengineering, Guilin University of Technology, Guilin, Guangxi 541006, PR China. Electronic address: liqiangyan@glut.edu.cn.

PMID: 31931356
DOI: 10.1016/j.saa.2020.118028

Abstract

A cleverish fluorescence probe based on coumarin was developed, exhibiting remarkable color change, strong fluorescence enhancement and fast response when it interacts with hydrazine in water solution. The limit of detection (LOD) is 5.59 × 10^-⁶ M for ultraviolet analysis and 8.18 × 10^-⁸ M for fluorescence analysis, respectively. Taking advantage of good sensitivity and short response time, the probe was applied to test hydrazine in water and to observe hydrazine in living cells.

Keywords: Cell imaging; Fluorescence probe; Hydrazine; Rapid detection.

MeSH terms

A549 Cells
Colorimetry
Coumarins / chemistry*
Fluorescent Dyes / chemistry*
Humans
Hydrazines / analysis*
Limit of Detection
Microscopy, Confocal
Microscopy, Fluorescence
Models, Molecular
Optical Imaging
Spectrometry, Fluorescence
Water / analysis

Substances

Coumarins
Fluorescent Dyes
Hydrazines
Water
hydrazine
coumarin