Dramatic Improvement of a Massive Plexiform Neurofibroma After Administration of Selumetinib

Pediatr Neurol. 2020 Apr:105:69-70. doi: 10.1016/j.pediatrneurol.2019.11.010. Epub 2019 Nov 30.
No abstract available

Keywords: Giant; Neoplasm; Plexiform neurofibroma; Selumetinib; Treatment.

Publication types

  • Case Reports
  • Letter

MeSH terms

  • Adolescent
  • Antineoplastic Agents / pharmacology*
  • Benzimidazoles / pharmacology*
  • Humans
  • Lower Extremity / pathology*
  • Male
  • Mitogen-Activated Protein Kinase Kinases / antagonists & inhibitors*
  • Neurofibroma, Plexiform / drug therapy*
  • Neurofibroma, Plexiform / etiology
  • Neurofibroma, Plexiform / pathology
  • Neurofibromatosis 1 / complications*

Substances

  • AZD 6244
  • Antineoplastic Agents
  • Benzimidazoles
  • Mitogen-Activated Protein Kinase Kinases