Hexagonal Boron Nitrides (White Graphene): A Promising Method for Cancer Drug Delivery

Int J Nanomedicine. 2019 Dec 19:14:9983-9993. doi: 10.2147/IJN.S205095. eCollection 2019.

Abstract

Advances in low-dimensions nanomaterials drug-carrier have rapidly translated into clinical practice. Interestingly, the two-dimensional (2D) nanomaterials of hexagonal boron nitride (h-BN), so-called "white graphite" are relatively less explored compared to the post popular 2D graphene oxide (GO). However, the unique properties of h-BN nanomaterials make them well suited for the delivery of chemotherapeutic in cancer treatment. Recent studies have shown that the h-BN is a potential candidate in biomedical sciences, both as nanocarriers and nano-transducers. In this review, we discuss the various physicochemical properties and important concepts involved in h-BN nanosheets as anticancer drug carriers.

Keywords: anticancer drug delivery; biomaterials; biomedical potentiality; functionalization; h-BN.

Publication types

  • Review

MeSH terms

  • Antineoplastic Agents / administration & dosage*
  • Boron Compounds / chemistry*
  • Drug Carriers / administration & dosage
  • Drug Carriers / chemistry
  • Drug Delivery Systems / methods*
  • Humans
  • Nanostructures / administration & dosage*
  • Nanostructures / chemistry*
  • Neoplasms / drug therapy

Substances

  • Antineoplastic Agents
  • Boron Compounds
  • Drug Carriers
  • boron nitride