Chemical Constituents and Bioactivities of Starfishes: An Update

Chem Biodivers. 2020 Jan;17(1):e1900638. doi: 10.1002/cbdv.201900638. Epub 2020 Jan 7.

Abstract

Starfishes produce various structurally unique secondary metabolites with diverse biological activities. This review is an update summary of the new compounds and their bioactivities from starfish (the Asteroidea Class) with 71 references covering from January 2007 to December 2018. During this period, 216 new compounds were obtained from 36 species. The chemical constituents are mostly steroids, steroidal glycosides, and gangliosides. These components have been found to possess various bioactivities, including anticancer, anti-inflammation, etc.

Keywords: biological activity; glycosides; secondary metabolites; starfishes; steroids.

Publication types

  • Review

MeSH terms

  • Animals
  • Anti-Inflammatory Agents / chemistry
  • Anti-Inflammatory Agents / isolation & purification
  • Anti-Inflammatory Agents / pharmacology*
  • Antineoplastic Agents, Phytogenic / chemistry
  • Antineoplastic Agents, Phytogenic / isolation & purification
  • Antineoplastic Agents, Phytogenic / pharmacology*
  • Humans
  • Inflammation / drug therapy*
  • Neoplasms / drug therapy*
  • Starfish / chemistry*

Substances

  • Anti-Inflammatory Agents
  • Antineoplastic Agents, Phytogenic