Influence of propofol-based total intravenous anaesthesia on peri-operative outcome measures: a narrative review

Anaesthesia. 2020 Jan:75 Suppl 1:e90-e100. doi: 10.1111/anae.14905.

Abstract

Propofol-based total intravenous anaesthesia is well known for its smooth, clear-headed recovery and anti-emetic properties, but there are also many lesser known beneficial properties that can potentially influence surgical outcome. We will discuss the anti-oxidant, anti-inflammatory and immunomodulatory effects of propofol and their roles in pain, organ protection and immunity. We will also discuss the use of propofol in cancer surgery, neurosurgery and older patients.

Keywords: anaesthesia; cancer; intravenous; pain; propofol; surgery.

Publication types

  • Review

MeSH terms

  • Anesthesia, Intravenous / methods*
  • Anesthetics, Intravenous*
  • Humans
  • Patient Outcome Assessment*
  • Perioperative Period*
  • Propofol*

Substances

  • Anesthetics, Intravenous
  • Propofol