A new perspective in cancer immunotherapy: PD-1 on myeloid cells takes center stage in orchestrating immune checkpoint blockade

Sci Immunol. 2020 Jan 3;5(43):eaaz8128. doi: 10.1126/sciimmunol.aaz8128.

Abstract

PD-1 mediates antitumor immunity by regulating lineage fate commitment and function of myeloid cells (see related Research Article by Strauss et al..).

Publication types

  • Review
  • Comment

MeSH terms

  • Humans
  • Immunotherapy
  • Myeloid Cells
  • Neoplasms*
  • Programmed Cell Death 1 Receptor*

Substances

  • Programmed Cell Death 1 Receptor