Localization of common carotid artery transverse section in B-mode ultrasound images using faster RCNN: a deep learning approach

Med Biol Eng Comput. 2020 Mar;58(3):471-482. doi: 10.1007/s11517-019-02099-3. Epub 2020 Jan 2.

Abstract

Cardiologists can acquire important information related to patients' cardiac health using carotid artery stiffness, its lumen diameter (LD), and its carotid intima-media thickness (cIMT). The sonographers primarily concern about the location of the artery in B-mode ultrasound images. Localization using manual methods is tedious and time-consuming and also may lead to some errors. On the other hand, automated approaches are more objective and can provide the localization of the artery at near real time. Above arterial parameters may be determined after localization of the artery in real time.A novel method of localization of common carotid artery (CCA) transverse section is presented in this work. The method is known as fast region convolutional neural network (FRCNN)-based localization method and is designed using a stack of three layers viz. convolutional layers, fully connected layers, and pooling layers. These organized layers constitute a region proposal network (RPN) and an object class detection network (OCDN). We obtain an outcome as a bounding box along with a score of prediction around the cross-section of the CCA.B-mode ultrasound image database of CCA is split into training and testing set, to accomplish this, three partition methods K = 2, 5, and 10 are used in our work. The training is extended for 30, 200, and 2000 epochs in order to achieve fine-tuned features from the convolutional neural network. After 2000 epochs, we obtain 95% validation accuracy; however, mean of the accuracies up to 2000 epochs is 89.36% for K = 10 partitions protocol (training 90%, testing 10%). Generated CNN model is tested on a different dataset of 433 images and the acquired accuracy is 87.99%. Thus, the proposed method including an advanced deep learning technique demonstrates promising localization for carotid artery transverse section. Graphical abstract.

Keywords: B-mode ultrasound; Bounding box; CCA; Convolutional neural network (CNN); FRCNN.

MeSH terms

  • Algorithms
  • Benchmarking
  • Carotid Arteries / diagnostic imaging*
  • Deep Learning*
  • Humans
  • Image Processing, Computer-Assisted
  • Neural Networks, Computer*
  • Reproducibility of Results
  • Ultrasonography*