Population data for 23 Y chromosome STR loci using the Powerplex® Y23 STR kit for the Kedayan population in Malaysia

Int J Legal Med. 2020 Jul;134(4):1335-1337. doi: 10.1007/s00414-019-02237-4. Epub 2020 Jan 2.

Abstract

Genetic polymorphisms at 23 Y chromosome short tandem repeat (STRs) loci included in the Powerplex® Y23 PCR kit were successfully scored in 128 unrelated Kedayan individuals living in Sabah, East Malaysia. Complete haplotypes were recorded for all individuals and included 92 different types with 72 being unique to single male subjects. Three important forensic statistics were calculated from these data; haplotype diversity = 0.993, discriminating capacity = 0.719, and match probability = 0.015. The Kedayan appear to be most closely related to Malays and Filipinos in a multidimensional scaling plot and are separated from other mainland Asia populations including Thais and Hakka Han. These new data for Kedayan have been deposited in the YHRD database (accession number: YA004621). Our statistical analyses showed the reliability of Y-STR loci for geographically extended use in forensic casework and for studying human population history.

Keywords: Haplotypes; Kedayan; Malaysia; Population genetic; Powerplex® Y23 system; Y chromosome STR.

MeSH terms

  • Chromosomes, Human, Y*
  • Ethnicity / genetics*
  • Gene Frequency*
  • Haplotypes*
  • Humans
  • Malaysia / ethnology
  • Male
  • Microsatellite Repeats*
  • Multidimensional Scaling Analysis
  • Polymorphism, Genetic*
  • Sequence Analysis, DNA