Long-term survival of an advanced colorectal cancer patient treated with Regorafenib: Case report and literature review

Oronzo Brunetti; Angela Calabrese; Loredana Palermo; Antonio Giovanni Solimando; Antonella Argentiero

doi:10.1002/ccr3.2496

Long-term survival of an advanced colorectal cancer patient treated with Regorafenib: Case report and literature review

Clin Case Rep. 2019 Oct 24;7(12):2379-2383. doi: 10.1002/ccr3.2496. eCollection 2019 Dec.

Authors

Oronzo Brunetti¹, Angela Calabrese², Loredana Palermo¹, Antonio Giovanni Solimando^{1

3}, Antonella Argentiero¹

Affiliations

¹ Medical Oncology Unit IRCCS Istituto Tumori "Giovanni Paolo II" Bari Italy.
² Radiology Unit IRCCS Istituto Tumori "Giovanni Paolo II" Bari Italy.
³ Department of Biomedical Sciences and Human Oncology Section of Internal Medicine "G. Baccelli" University of Bari Medical School Bari Italy.

Abstract

Two phase 3 trials reported a prolonged survival in the third-line setting of colorectal cancer patients treated with regorafenib with the longest duration of treatment of 16 months. Herein, we reported a unique case of a patient refractory to conventional chemotherapy who showed a prolonged stable disease with regorafenib.

Keywords: colorectal cancer; long‐term survival; regorafenib.

Publication types

Case Reports