Hybrid Graphene/Conducting Polymer Strip Sensors for Sensitive and Selective Electrochemical Detection of Serotonin

Wed Al-Graiti; Javad Foroughi; Yuqing Liu; Jun Chen

doi:10.1021/acsomega.9b03456

Hybrid Graphene/Conducting Polymer Strip Sensors for Sensitive and Selective Electrochemical Detection of Serotonin

ACS Omega. 2019 Dec 16;4(26):22169-22177. doi: 10.1021/acsomega.9b03456. eCollection 2019 Dec 24.

Authors

Wed Al-Graiti^{1

2}, Javad Foroughi^{1

1}, Yuqing Liu¹, Jun Chen¹

Affiliations

¹ Intelligent Polymer Research Institute, and School of Electrical, Computer and Telecommunications Engineering, Faculty of Engineering and Information Sciences, University of Wollongong, Wollongong, New South Wales 2522, Australia.
² Chemistry Department, Science College, Thi-Qar University, Thi-Qar, Iraq.

Abstract

There is an urgent need for electrochemical sensor materials that exhibit electrochemically compliant properties while also retaining high durability under physiological conditions. Herein, we demonstrate a novel strip-style electrochemical sensor using reduced graphene oxide (rGO) and poly(ethylene dioxythiophene)/poly(styrene sulfonic acid) (PEDOT/PSS) nanocomposite films. The fabricated rGO-PEDOT/PSS sensor with and without nafion has shown an effective electrochemical response for both selectivity and sensitivity of the serotonin (5-hydroxytryptamine, 5-HT) neurotransmitter. The developed high-performance hybrid graphene/conducting polymer strip sensors are likely to find applications as chip electrochemical sensor devices for patients diagnosed with Alzheimer's disease.