Prevalance of Celiac Disease in Patients with Inflammatory Bowel Disease in Turkish Population

Göksel Bengi; Musa Cıvak; Mesut Akarsu; Müjde Soytürk; Ender Ellidokuz; Ömer Topalak; Hale Akpınar

doi:10.1155/2019/6272098

Prevalance of Celiac Disease in Patients with Inflammatory Bowel Disease in Turkish Population

Gastroenterol Res Pract. 2019 Dec 11:2019:6272098. doi: 10.1155/2019/6272098. eCollection 2019.

Authors

Göksel Bengi¹, Musa Cıvak², Mesut Akarsu¹, Müjde Soytürk¹, Ender Ellidokuz¹, Ömer Topalak¹, Hale Akpınar¹

Affiliations

¹ Gastroenterology Unit, Department of Internal Medicine, Dokuz Eylül University, İzmir, Turkey.
² Department of Internal Medicine, Dokuz Eylül University, İzmir, Turkey.

Abstract

Background: Celiac disease (CD) and inflammatory bowel disease (IBD) involve inflammation of the gastrointestinal lumen, which environmental, genetic, and immunological factors have a role in their pathogenesis. The prevalence of celiac disease in IBD ranges from 0% to 14%. In this study, our aim was to determine the prevalence of CD in IBD patients followed by us who are attending the hospital or outpatient clinic over a period of time of seven years.

Methods: Seven hundred and fifty nine patients (425 M, 334 F, mean age: 46.75, 396 ulcerative colitis (UC), 363 Crohn's disease (CrD)) diagnosed and followed up for IBD between January 2009 and July 2016 were evaluated retrospectively, and clinical, demographic, laboratory, and endoscopic data were collected.

Results: CD was investigated in 79 (%10.4) inflammatory bowel disease patients according to symptoms, and in 5.06% (n = 4) of them, we diagnosed CD. The most common indication for investigating for CD was iron deficiency anemia unreponsive to iron supplementation.

Conclusions: We did not find an increased prevalance of celiac disease in Turkish IBD patients in this study. In the presence of refractory iron deficiency anemia without any other cause in IBD patients, investigations for celiac disease should be considered.