Nano-Based Drug Delivery System: Recent Strategies for the Treatment of Ocular Disease and Future Perspective

Abstract

The structure of the eye is very complex in nature which makes it a challenging task for pharmaceutical researchers to deliver the drug at the desired sites via different routes of administration. The development of the nano-based system helped in delivering the drug in the desired concentration. Improvement in penetration property, bioavailability, and residence time has all been achieved by encapsulating drugs into liposomes, dendrimers, solid lipid nanoparticle, nanostructured lipid carrier, nanoemulsion, and nanosuspension. This review puts emphasis on the need for nanomedicine for ocular drug delivery and recent developments in the field of nanomedicine along with recent patents published in the past few years.

Keywords: Ocular drug delivery system; hydrogels; inorganic nanoparticles; nanoemulsion; nanomedicine; nanostructured lipid carriers; patents; solid lipid nanocarriers..