Bihemisphere Ischemia Due to a Unilateral Lesion: A Case Report

J Stroke Cerebrovasc Dis. 2020 Apr;29(4):104590. doi: 10.1016/j.jstrokecerebrovasdis.2019.104590. Epub 2019 Dec 26.

Abstract

Bihemispheric ischemic strokes secondary to unilateral vessel disease are uncommon. We present the case of a 70-year-old man with multiple acute/subacute bilateral infarcts. The patient was found to have stenosis of the left internal carotid artery secondary to herpes zoster ophthalmicus vasculopathy, with involvement of the left proximal middle and anterior cerebral arteries. Angiographic studies also revealed A1 segment aplasia of the right anterior cerebral artery (ACA), thus indicating dependence on the left-sided circulation for perfusion of the bilateral ACA vascular territory. This case illustrates how A1 segment aplasia, an anatomic variant of the circle of Willis detected by angiographic studies, can contribute to bilateral infarction in the ACA vascular territory.

Keywords: Bihemispheric ischemia; anatomic variation; anterior cerebral artery; circle of Willis; herpes zoster ophthalmicus; stroke.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Anterior Cerebral Artery / abnormalities*
  • Anterior Cerebral Artery / diagnostic imaging
  • Anterior Cerebral Artery / physiopathology
  • Carotid Artery, Internal* / diagnostic imaging
  • Carotid Artery, Internal* / physiopathology
  • Carotid Stenosis / complications*
  • Carotid Stenosis / diagnostic imaging
  • Carotid Stenosis / physiopathology
  • Cerebrovascular Circulation
  • Cerebrum / blood supply*
  • Circle of Willis / abnormalities*
  • Circle of Willis / diagnostic imaging
  • Circle of Willis / physiopathology
  • Humans
  • Infarction, Anterior Cerebral Artery / diagnostic imaging
  • Infarction, Anterior Cerebral Artery / etiology*
  • Infarction, Anterior Cerebral Artery / physiopathology
  • Infarction, Middle Cerebral Artery / diagnostic imaging
  • Infarction, Middle Cerebral Artery / etiology*
  • Infarction, Middle Cerebral Artery / physiopathology
  • Male
  • Middle Cerebral Artery* / diagnostic imaging
  • Middle Cerebral Artery* / physiopathology