Transient pulmonary nodules with halo sign in patients with advanced heart failure: a report of two cases

Clin Imaging. 2020 Mar;60(1):90-94. doi: 10.1016/j.clinimag.2019.11.008. Epub 2019 Nov 27.

Abstract

Rationale and objectives: Imaging is important in the diagnosis and follow-up of patients with heart failure (HF). Several thoracic radiological features have been described in these patients. The nodules with halo sign are very rarely reported in HF patients. This sign can appear in several diseases and a clinical context is essential for a final diagnosis.

Materials and methods: We present two immunocompetent patients with advanced HF waiting for cardiac transplantation showing multiple transient lung nodules with halo sign on preoperative chest CT.

Results: Our patients showed mild interstitial pulmonary edema and more interestingly multiple transient pulmonary nodules with halo sign. These nodules didn't coalesce, they even appear and disappear rapidly during worsening of pulmonary edema and showed thick halos. Nodules with halo sign are rarely reported in heart failure and considered focal pulmonary edema.

Conclusion: Nodules with halo sign in patients with advanced heart failure are a not usual finding that could not be the result of focal pulmonary edema, but of hemorrhage.

Keywords: Halo sign; Heart failure; Lung diseases; Tomography; X-ray computed.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Female
  • Heart Failure
  • Hemorrhage
  • Humans
  • Male
  • Middle Aged
  • Multiple Pulmonary Nodules / diagnostic imaging*
  • Radiography, Thoracic / methods
  • Tomography, X-Ray Computed / methods