Image-based screening for men at high risk for breast cancer: Benefits and drawbacks

Ryan W Woods; Lonie R Salkowski; Mai Elezaby; Elizabeth S Burnside; Roberta M Strigel; Amy M Fowler

doi:10.1016/j.clinimag.2019.11.005

Image-based screening for men at high risk for breast cancer: Benefits and drawbacks

Clin Imaging. 2020 Mar;60(1):84-89. doi: 10.1016/j.clinimag.2019.11.005. Epub 2019 Nov 28.

Authors

Ryan W Woods¹, Lonie R Salkowski², Mai Elezaby³, Elizabeth S Burnside³, Roberta M Strigel⁴, Amy M Fowler⁴

Affiliations

¹ Department of Radiology, University of Wisconsin School of Medicine and Public Health, 600 Highland Avenue, Madison, WI 53792, USA. Electronic address: rwoods@uwhealth.org.
² Department of Radiology, University of Wisconsin School of Medicine and Public Health, 600 Highland Avenue, Madison, WI 53792, USA; Department of Medical Physics, University of Wisconsin School of Medicine and Public Health, 1111 Highland Avenue, Madison, WI 53705, USA.
³ Department of Radiology, University of Wisconsin School of Medicine and Public Health, 600 Highland Avenue, Madison, WI 53792, USA.
⁴ Department of Radiology, University of Wisconsin School of Medicine and Public Health, 600 Highland Avenue, Madison, WI 53792, USA; University of Wisconsin Carbone Cancer Center, 600 Highland Avenue, Madison, WI 53792, USA; Department of Medical Physics, University of Wisconsin School of Medicine and Public Health, 1111 Highland Avenue, Madison, WI 53705, USA.

Abstract

Male breast cancer is a rare malignancy. Due to low prevalence and limited data to support male breast cancer screening, there are currently no recommendations for image-based screening in asymptomatic men and few recommendations for men at high risk for breast cancer. However, symptomatically diagnosed cancers in men are typically advanced, suggesting that earlier detection may improve outcomes. In this article we briefly review the risk factors for male breast cancer, and discuss the potential benefits and possible drawbacks of routine image-based screening for men at high risk for breast cancer.

Keywords: BRCA 1, 2; Male breast cancer; Mammography; Risk factors; Screening.

Publication types

Review

MeSH terms

Adult
Breast Neoplasms / diagnostic imaging
Breast Neoplasms / epidemiology
Breast Neoplasms / pathology
Breast Neoplasms, Male / diagnostic imaging*
Breast Neoplasms, Male / epidemiology
Early Detection of Cancer
Female
Humans
Male
Mammography
Mass Screening
Middle Aged
Risk Factors

Abstract

Publication types

MeSH terms

Grants and funding