A winter to remember! Extracorporeal membrane oxygenation for life-threatening asthma in children: A case series and review of literature

Pediatr Pulmonol. 2020 Feb;55(2):E1-E4. doi: 10.1002/ppul.24616. Epub 2019 Dec 20.

Abstract

Progressive refractory near-fatal asthma requiring intubation and mechanical ventilation can lead to death. Data on outcomes in children requiring extracorporeal membrane oxygenation (ECMO) support for status asthmaticus is sparse. We describe our experience of three patients in the winter of 2018 to 2019 successfully rescued with ECMO. We also report our novel use of extubation while still being on ECMO support. Awareness and use of ECMO in refractory asthma can help lower the mortality for this very common disease in children. We also review the current literature on the use of ECMO and other extracorporeal therapies in asthma.

Keywords: ECMO; asthma; near fatal asthma; refractory asthma.

Publication types

  • Review

MeSH terms

  • Airway Extubation
  • Asthma*
  • Child
  • Extracorporeal Membrane Oxygenation*
  • Female
  • Humans
  • Male
  • Research Design
  • Respiration, Artificial
  • Status Asthmaticus