Culture-negative periprosthetic joint infection: is there a diagnostic role for next-generation sequencing?

Expert Rev Mol Diagn. 2020 Mar;20(3):269-272. doi: 10.1080/14737159.2020.1707080. Epub 2019 Dec 24.

Authors

Karan Goswami¹, Javad Parvizi¹

Affiliation

¹ Rothman Orthopaedic Institute, Thomas Jefferson University, Philadelphia, PA, USA.

PMID: 31858850
DOI: 10.1080/14737159.2020.1707080

No abstract available

Keywords: Culture-negative; Infection; Joint arthroplasty; Metagenomic sequencing; Next-generation sequencing; Periprosthetic joint infection.

Publication types

Editorial
Introductory Journal Article

MeSH terms

Arthritis, Infectious / diagnosis*
Arthritis, Infectious / etiology*
Disease Management
Disease Susceptibility
High-Throughput Nucleotide Sequencing
Humans
Metagenomics / methods
Molecular Diagnostic Techniques
Prosthesis-Related Infections / diagnosis*
Prosthesis-Related Infections / etiology*