[Advances in research on the pathogenesis of hydrocephalus]

Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2019 Oct 28;44(10):1188-1195. doi: 10.11817/j.issn.1672-7347.2019.180662.
[Article in Chinese]

Abstract

Hydrocephalus is a common neurological disease with complex etiology. It is characterized by the accumulation and continuous growth of cerebrospinal fluid in the ventricular system and subarachnoid space. Hydrocephalus can be caused by congenital genetic factors, brain trauma and cerebral hemorrhage. Through the efforts of many researchers, the pathogenesis of hydrocephalus is being completed, but it has not been fully explained. The imbalance of cerebrospinal fluid production and absorption into the sinus, and disorder of the cerebrospinal fluid circulation pathway or the osmotic pressure maintenance in the ventricle can lead to increased cerebrospinal fluid and ventricular dilatation.

脑积水是一种常见但病因复杂的神经系统疾病,以脑脊液在脑室系统及蛛网膜下腔内聚积并不断增长为特征,既可由先天性遗传因素导致,也可由后天脑外伤、脑出血等疾病诱发。脑脊液的产生与被吸收进入静脉窦的不平衡、脑脊液循环通路受阻或者脑室内渗透压维持功能紊乱均能导致脑脊液增多、脑室扩张。.

MeSH terms

  • Cerebral Hemorrhage
  • Cerebral Ventricles
  • Cerebrospinal Fluid
  • Humans
  • Hydrocephalus*