Investigating the effectiveness and cost-effectiveness of FITNET-NHS (Fatigue In Teenagers on the interNET in the NHS) compared to activity management to treat paediatric chronic fatigue syndrome (CFS)/myalgic encephalomyelitis (ME): amendment to the published protocol

Emma Anderson; Daisy Gaunt; Chris Metcalfe; Manmita Rai; William Hollingworth; Nicola Mills; Lucy Beasant; Roxanne Parslow; David Kessler; John Macleod; Paul Stallard; Hans Knoop; Elise Van de Putte; Sanne Nijhof; Gijs Bleijenberg; Esther Crawley

doi:10.1186/s13063-019-3895-1

Investigating the effectiveness and cost-effectiveness of FITNET-NHS (Fatigue In Teenagers on the interNET in the NHS) compared to activity management to treat paediatric chronic fatigue syndrome (CFS)/myalgic encephalomyelitis (ME): amendment to the published protocol

Trials. 2019 Dec 19;20(1):750. doi: 10.1186/s13063-019-3895-1.

Authors

Emma Anderson¹, Daisy Gaunt^{2

3}, Chris Metcalfe^{2

3}, Manmita Rai⁴, William Hollingworth², Nicola Mills², Lucy Beasant⁴, Roxanne Parslow⁴, David Kessler⁵, John Macleod⁵, Paul Stallard⁶, Hans Knoop⁷, Elise Van de Putte⁸, Sanne Nijhof⁸, Gijs Bleijenberg⁹, Esther Crawley⁴

Affiliations

¹ Centre for Child Health, Bristol Medical School: Population Health Sciences, University of Bristol, 1-5 Whiteladies Road, Bristol, BS8 1NU, UK. Emma.Anderson@bristol.ac.uk.
² Bristol Medical School: Population Health Sciences, University of Bristol, Canynge Hall, 39 Whatley Road, Bristol, BS8 2PS, UK.
³ Bristol Randomised Trials Collaboration, University of Bristol, Bristol, UK.
⁴ Centre for Child Health, Bristol Medical School: Population Health Sciences, University of Bristol, 1-5 Whiteladies Road, Bristol, BS8 1NU, UK.
⁵ Bristol Medical School: Population Health Sciences, Oakfield House, Oakfield Grove, Bristol, BS8 2BN, UK.
⁶ Department for Health, University of Bath, Bath, BA2 7AD, UK.
⁷ Department for Medical Psychology, University Medical Centres Amsterdam, University of Amsterdam, Postbox 22660, 1100 DD, Amsterdam, The Netherlands.
⁸ Department of Paediatrics, Wilhelmina Children's Hospital, University Medical Centre, Utrecht, The Netherlands.
⁹ Radboud University Medical Center, Nijmegen, The Netherlands.

Abstract

The FITNET-NHS Trial is a UK, national, trial investigating whether an online cognitive behavioural therapy program (FITNET-NHS) for treating chronic fatigue syndrome/ME in adolescents is clinically effective and cost-effective in the NHS. At the time of writing (September 2019), the trial was recruiting participants. This article presents an update to the planned sample size and data collection duration previously published within the trial protocol. TRIAL REGISTRATION: ISRCTN, ID: 18020851. Registered 8 April 2016.

Keywords: CBT; CFS/ME; Chronic fatigue syndrome; E-therapy; Methodology; Myalgic encephalomyelitis; Online systems; Paediatrics; Recruitment; Trial.

Publication types

Clinical Trial Protocol
Letter

MeSH terms

Adolescent
Child
Cognitive Behavioral Therapy / economics
Cognitive Behavioral Therapy / methods*
Cost-Benefit Analysis*
Fatigue Syndrome, Chronic / diagnosis
Fatigue Syndrome, Chronic / economics
Fatigue Syndrome, Chronic / therapy*
Female
Health Surveys / statistics & numerical data
Humans
Internet-Based Intervention / economics*
Male
Randomized Controlled Trials as Topic
Sample Size
State Medicine / economics
Treatment Outcome
United Kingdom

Abstract

Publication types

MeSH terms

Grants and funding