Carbapenem-Susceptible Klebsiella pneumoniae and Escherichia coli Isolates Carrying a Truncated KPC Carbapenemase: a Challenge for Rapid Molecular Diagnostics

J Clin Microbiol. 2020 Feb 24;58(3):e01627-19. doi: 10.1128/JCM.01627-19. Print 2020 Feb 24.

Hossein Salimnia¹, Jennifer Veltman¹, Pranatharthi H Chandrasekar¹, Jason M Pogue², Ryan Mynatt², Tanaz Salimnia³, Steven H Marshall⁴, Andrea M Hujer^{4

5}, Robert A Bonomo^{6

5

7

8

9

10

11

12}

¹ Wayne State University School of Medicine, Detroit, Michigan, USA.
² Detroit Medical Center, Detroit, Michigan, USA.
³ Wayne State University School of Medicine, Rochester Hills, Michigan, USA.
⁴ Louis Stokes Cleveland Department of Veterans Affairs Medical Center, Cleveland, Ohio, USA.
⁵ Department of Medicine, Case Western Reserve University, Cleveland, Ohio, USA.
⁶ Louis Stokes Cleveland Department of Veterans Affairs Medical Center, Cleveland, Ohio, USA robert.bonomo@va.gov.
⁷ Geriatric Research, Education, and Clinical Center, Louis Stokes Cleveland Department of Veterans Affairs Medical Center, Cleveland, Ohio, USA.
⁸ Department of Pharmacology, Case Western Reserve University, Cleveland, Ohio, USA.
⁹ Department of Molecular Biology & Microbiology, Case Western Reserve University, Cleveland, Ohio, USA.
¹⁰ CWRU-Cleveland VAMC Center for Antimicrobial Resistance and Epidemiology (Case VA CARES), Cleveland, Ohio, USA.
¹¹ Department of Biochemistry, Case Western Reserve University, Cleveland, Ohio, USA.
¹² Department of Proteomics & Bioinformatics, Case Western Reserve University, Cleveland, Ohio, USA.

No abstract available

Keywords: Escherichia coli; KPC; Klebsiella pneumoniae; carbapenemase; rapid molecular diagnostics; truncation.

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