Compressive myelopathy and compression fracture of aggressive vertebral hemangioma after parturition: A case report and review of literature

Medicine (Baltimore). 2019 Dec;98(50):e18285. doi: 10.1097/MD.0000000000018285.

Abstract

Rationale: Compressive myelopathy and compression fracture of aggressive vertebral hemangioma after parturition is a rare condition. Vertebral body compression fracture and high serum progesterone lead to extraosseous hemangioma enlargment cause narrowing the spinal canal which contribute to compressive myelopathy relate to pregnancy.

Patient concerns: We report a case of compressive myelopathy and compression fracture of aggressive vertebral hemangioma after parturition in a 35-year-old woman. The patient complained unable to walk and experienced intense pain in the back.

Diagnosis: Based on the clinical features and imaging studies, the patient underwent a T4-T6 laminectomy. Histopathology consistent with vertebral hemangioma.

Interventions: The patient underwent laminectomy for decompression. After subperiosteal dissection of the paraspinal muscles and exposure of the laminae, there was no involvement of the lamina by the tumor. The epidural tumor was removed through the spaces lateral to the thecal sac. Vertebroplasty was performed through T5 pedicles bilaterally and 7 ml of polymethylmethacrylate (PMMA) cement was injected. T4-T6 pedicle screw fixation was performed for segmental fixation and fusion.

Outcomes: Six months after resection of the tumor the patient remained asymptomatic. She reported no low back pain and had returned to her normal daily activities, with no radiographic evidence of recurrence on MRI. Physical examination revealed that superficial and deep sensation was restored to normal levels in the lower extremities.

Lessons: The occurrence of compressive myelopathy of pregnancy related vertebral hemangiomas is quite unusual. It can lead to serious neurologic deficits if not treated immediately. So, prompt diagnosis is important in planning optimal therapy and preventing morbidity for patients.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adult
  • Decompression, Surgical / methods
  • Female
  • Fractures, Compression / complications*
  • Fractures, Compression / diagnosis
  • Fractures, Compression / surgery
  • Hemangioma / complications*
  • Hemangioma / diagnosis
  • Hemangioma / surgery
  • Humans
  • Magnetic Resonance Imaging
  • Parturition*
  • Positron Emission Tomography Computed Tomography
  • Spinal Cord Compression / diagnosis
  • Spinal Cord Compression / etiology*
  • Spinal Cord Compression / surgery
  • Spinal Fractures / complications*
  • Spinal Fractures / diagnosis
  • Spinal Fractures / surgery
  • Spinal Neoplasms / complications*
  • Spinal Neoplasms / diagnosis
  • Spinal Neoplasms / surgery
  • Thoracic Vertebrae*
  • Vertebroplasty / methods