Liver function testing in a working population: three strategies to reduce false-positive results

J Occup Med. 1988 Sep;30(9):693-7.

Abstract

A very high rate of mildly abnormal results on a liver panel of five serum chemistries was observed when these tests were performed on a group of asymptomatic, normal workers. These results often led to lengthy delays in hiring, which benefited neither worker nor employer. Three strategies which markedly reduce the number of false-positive examinations with little or no reduction in test sensitivity are available.

MeSH terms

  • False Positive Reactions
  • Humans
  • Liver Diseases / blood
  • Liver Diseases / diagnosis*
  • Liver Function Tests*
  • Occupational Diseases / blood
  • Occupational Diseases / diagnosis*
  • Occupational Medicine
  • Reference Standards
  • Reference Values