Up-regulation of miR-338-5p after spinal cord injury enhances the neuronal repair via inhibition of inflammation aggravation and oxidative stress

Minerva Med. 2021 Aug;112(4):533-534. doi: 10.23736/S0026-4806.19.06280-3. Epub 2019 Dec 13.

Authors

Xiaoqi Dai¹, Zhenhua Cai¹, Jinfeng Liu²

Affiliations

¹ Department of Pain, The Second Hospital Affiliated to Harbin Medical University, Harbin, China.
² Department of Pain, The Second Hospital Affiliated to Harbin Medical University, Harbin, China - mzliujf2004@126.com.

PMID: 31833735
DOI: 10.23736/S0026-4806.19.06280-3

No abstract available

Publication types

Letter

MeSH terms

Angiopoietin-1 / metabolism*
Animals
Disease Models, Animal
Heme Oxygenase (Decyclizing) / metabolism
Interleukin-1beta / metabolism
Interleukin-6 / metabolism
Interleukins / metabolism
Lipid Peroxidation
MicroRNAs / administration & dosage
MicroRNAs / metabolism*
Microglia / metabolism
Myelitis / metabolism
Nerve Growth Factor / metabolism
Nerve Growth Factors / metabolism
Neuroglia / metabolism*
Neuroglia / physiology
Neurons / metabolism
Oxidative Stress*
Rats
Rats, Sprague-Dawley
Recovery of Function
Spinal Cord Injuries / metabolism*
Spinal Cord Injuries / physiopathology
Time Factors
Transfection
Up-Regulation

Substances

Angiopoietin-1
Angpt1 protein, rat
Interleukin-1beta
Interleukin-6
Interleukins
MIRN338 microRNA, rat
MicroRNAs
Nerve Growth Factors
Ngf protein, rat
Nerve Growth Factor
Heme Oxygenase (Decyclizing)
Hmox1 protein, rat