Expanding the capillary electrophoresis-based glucose unit database of the GUcal app

Gabor Jarvas; Marton Szigeti; Matthew P Campbell; Andras Guttman

doi:10.1093/glycob/cwz102

Expanding the capillary electrophoresis-based glucose unit database of the GUcal app

Glycobiology. 2020 May 19;30(6):362-364. doi: 10.1093/glycob/cwz102.

Authors

Gabor Jarvas^{1

2}, Marton Szigeti¹, Matthew P Campbell³, Andras Guttman^{1

2}

Affiliations

¹ Translational Glycomics Group, Research Institute of Biomolecular and Chemical Engineering, University of Pannonia, 10 Egyetem, Veszprem 8200, Hungary.
² Horváth Csaba Memorial Laboratory of Bioseparation Sciences, Research Centre for Molecular Medicine, Faculty of Medicine, University of Debrecen, 98 Nagyerdei, Debrecen, 4032, Hungary.
³ Institute for Glycomics, Griffith University at Gold Coast, Southport, QLD 4215, Australia.

PMID: 31829415
DOI: 10.1093/glycob/cwz102

Abstract

GUcal is a standalone application for automatically calculating the glucose unit (GU) values for separated N-glycan components of interest in an electropherogram and suggests their tentative structures by utilizing an internal database. We have expanded the original database of GUcal by integrating all publicly available capillary electrophoresis (CE) data in the GlycoStore collection (https://www.glycostore.org) and with in-house measured GU values. The GUcal app is freely available online (https://www.gucal.hu) and readily facilitates CE-based high throughput GU value determination for first line structural elucidation.

Keywords: N-glycan; capillary electrophoresis; database; glucose unit; structure identification.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Databases, Factual
Electrophoresis, Capillary
Glucose / chemistry*
Humans
Polysaccharides / chemistry
Software*

Substances

Polysaccharides
Glucose