[Pregnancy and rheumatic diseases]

Z Rheumatol. 2020 Feb;79(1):55-73. doi: 10.1007/s00393-019-00736-8.
[Article in German]

Abstract

Inflammatory rheumatic diseases preferentially affect women of childbearing age. Immunological alterations can have positive or negative effects on the maternal disease. Most of these women can have a successful pregnancy with careful medical and obstetric care. Nevertheless, complications are more frequent than in healthy women. Pregnancies should therefore be planned during inactive phases of the disease and patients should be educated in advance about possible maternal and child risks and about treatment options compatible with pregnancy. In pregnancy, individualized and interdisciplinary care can promote a stable course of the disease and reduce the risks for mother and child. Especially with respect to a compatible treatment, detailed information for the patients is necessary for a shared decision making.

Keywords: Antirheumatic treatment; Pregnancy complications; Rheumatoid arthritis; Spondyloarthritis; Systemic lupus erythematosus.

MeSH terms

  • Child
  • Female
  • Humans
  • Pregnancy
  • Pregnancy Complications* / diagnosis
  • Pregnancy Complications* / drug therapy
  • Rheumatic Diseases* / complications
  • Rheumatic Diseases* / diagnosis
  • Rheumatic Diseases* / drug therapy