Metal-Free Insertion Reactions of Silanes with Aryldiazoacetates

J Org Chem. 2020 Jan 17;85(2):1240-1246. doi: 10.1021/acs.joc.9b02605. Epub 2019 Dec 23.

Abstract

Si-H insertion reactions represent an important method for the efficient construction of new C-Si bonds, and typically, they are conducted in the presence of metal catalysts. In this report, we describe a photochemical approach that now allows the insertion of carbenes into the Si-H bond of silanes under metal-free reaction conditions (23 examples, up to 83% yield).